MRPS31 anticorps (N-Term)
Aperçu rapide pour MRPS31 anticorps (N-Term) (ABIN2789214)
Antigène
Voir toutes MRPS31 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- LTVRHGTVRY RSSALLARTK NNIQRYFGTN SVICSKKDKQ SVRTEETSKE
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Homologie
- Human: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against MRPS31. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 395 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MRPS31 (Mitochondrial Ribosomal Protein S31 (MRPS31))
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Autre désignation
- MRPS31
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Sujet
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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes, however, its relationship to the etiology of this disease remains to be clarified. Pseudogenes corresponding to this gene have been found on chromosomes 3 and 13.
Alias Symbols: IMOGN38, MRP-S31, S31mt
Protein Interaction Partner: GRSF1, UBC, SMURF2, PARK2, STAT3, ESR2, SARNP, CPSF7, SRPRB, FLOT1, CUL3, ICT1, USP42, EIF6, LYST,
Protein Size: 395 -
Poids moléculaire
- 43 kDa
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ID gène
- 10240
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NCBI Accession
- NM_005830, NP_005821
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UniProt
- Q92665
Antigène
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